A genius chemist, Mixmaster serves as a weapons designer to the Decepticon elite. He has spent his entire lifespan mastering the intricacies of chemical reactions, becoming an expert in poisons, corrosive substances, and especially explosives. He has a knack for improvisation, being able to make deadly concoctions from just the native materials a world has to offer. A member of the Constructicons, and a Mixmaster clone is seen during the Egypt battle, and formed the head of Devastator, but the clone is killed by a railgun. Also the real Mixmaster is killed by Jetfire.
There are at least two 'clones of his model.